Materials used for indirect pulp treatment in primary teeth: a mixed treatment comparisons meta-analysis. Vital pulp treatment is indicated only when the clinical diagnosis of a reversible pulpitis is made. Purpose: The purpose of this protocol for a systematic review of randomized controlled trials of primary tooth vital pulp therapy is to describe the reasoning and need for the review, the objectives of the review, and the methodology that will be used to analyse data from the included studies. Currently, there are three vital pulp therapy (VPT) op-tions for treatment of deep dentin caries lesions approxi - mating the pulp in vital primary teeth viz. Moreover, factors According to current scientific opinion, in case of an irreversible pulpitis, a healing of the tissue cannot be predictably achieved after removing the triggering stimulus. 2020 Aug 25;9(9):2738. doi: 10.3390/jcm9092738. Semantic Scholar is a free, AI-powered research tool for scientific literature, based at the Allen Institute for AI. HHS Self-Limiting versus Rotary Subjective Carious Tissue Removal: A Randomized Controlled Clinical Trial-2-Year Results. Vital pulp therapy (VPT) is a potential alternative to root canal treatment (RC). Vital pulp therapies are the treatment of choice for traumatized and carious teeth with vital pulps and open apices [17].  |  NIH The fluctuation of the success rate of direct pulp capping was observed (>6 months-1 year, 87.5%; >1-2 years, 95.4%; >2-3 years, 87.7%; and >3 years, 72.9%). Is partial pulpotomy in cariously exposed posterior permanent teeth a viable treatment option? Copyright © 2011 American Association of Endodontists. The review is reported in accordance with the PRISMA Statement. Aust Endod J. Ali AH, Thani FB, Foschi F, Banerjee A, Mannocci F. J Clin Med. This systematic review aims to illustrate the outcome of vital pulp therapy, namely direct pulp capping, partial pulpotomy, and full pulpotomy, in vital permanent teeth with cariously exposed pulp… Current best evidence provides inconclusive information regarding factors influencing treatment outcome, and this emphasizes the need for further observational studies of high quality. Vital pulp therapy in cariously exposed permanent teeth and its limitations. MTA and biodentine for primary teeth pulpotomy: a systematic review and meta-analysis of clinical trials, A Survival Analysis of Different Pulp Therapies in Decayed Primary Teeth. Cariously exposed pulps may benefit from vital pulp therapies. This was based on an informal indirect comparison. Would you like email updates of new search results? Introduction: • Accepted endodontic therapy for primary teeth can be divided into two categories: vital pulp therapy (VPT) and root canal treatment (RCT). Outcomes of direct pulp capping in vital primary teeth with cariously and non-cariously exposed pulp: A systematic review. Sodium Hypochlorite Reduces Postoperative Discomfort and Painful Early Failure after Carious Exposure and Direct Pulp Capping-Initial Findings of a Randomized Controlled Trial. Evid Based Dent. eCollection 2020 May-Jun. The role of several players of the host response in pulpitis is well documented: cytokines, proteases, inflammatory mediators, Objective: The objective of this systematic review is to assess the literature regarding the efficacy of ... Vital Pulp Therapy AND Primary Molar AND Outcomes 12 5 4 Buckley’s Formocresol AND Pulpotomy AND Primary Molar AND Clinical OR Radiographic Success Rate 223 17 J Int Soc Prev Community Dent. Vital pulp therapy (VPT) is a potential alternative to root canal treatment (RC).2VPT is a restorative dental procedure that aims to treat teeth with compromised dental pulp without the full removal or excavation of all healthy pulp tissue.2It is commonly performed in primary dentition (also known as baby teeth), as primary dentition has not fully developed the apical root, but is less commonly performed in secondary … doi: 10.1016/j.joen.2019.07.005. There were 4 filed/granted patents, 2 systematic reviews/meta-analyses and 25 RCTs. indirect pulp cap, direct pulp cap (DPC) and pulpotomy (2). The selection of agent can influ-ence the success rate of vital-pulp therapy [3]. All statistics were performed by STATA version 10. The goal of VPT in primary teeth is to treat reversible pulpal injuries and maintaining pulp vitality. COVID-19 is an emerging, rapidly evolving situation. USA.gov. Vital Pulp Therapy: A Systematic Review and Meta-Analysis”9 is panel members discussed all recommendations and issues sur- the basis for the current guideline’s recommendations. Please enable it to take advantage of the complete set of features! Author information: (1)Preventive Dentistry, Periodontology and Cariology, Center for Dental Medicine, University of Zurich, 8032 Zurich, Switzerland. 2019 Nov;45(11):1296-1306.e3. Int J Environ Res Public Health. Objectives. Published by Elsevier Inc. All rights reserved. J Conserv Dent. Relative effectiveness of direct and indirect pulp capping in the primary dentition, Efficacy of Biodentine and Mineral Trioxide Aggregate in Primary Molar Pulpotomies—A Systematic Review and Meta‐Analysis With Trial Sequential Analysis of Randomized Clinical Trials. Indirect pulp therapy: an alternative to pulpotomy in primary teeth. The aim of this systematic review was to compare between pulpotomy and pulpectomy clinically and radiographically in the treatment of carious vital pulp exposure in primary incisors. Findings were comparable between vital pulp therapy and root canal or in favour of vital pulp therapy for short-term (one week) post-operative pain reduction. Partial pulpotomy and full pulpotomy sustained a high success rate up to more than 3 years (partial pulpotomy: >6 months-1 year, 97.6%; >1-2 years, 97.5%; >2-3 years, 97.6%; and >3 years, 99.4%; full pulpotomy: >6 months-1 year, 94%; >1-2 years, 94.9%; >2-3 years, 96.9%; and >3 years, 99.3%). Epub 2019 Sep 10. Vital pulp therapy plays a major role in the pre-servation of primary dentition after caries affliction (1). Well-designed, better powered randomized controlled trials are needed for more evidence; however, these studies show that there is good long-term prognosis of vital pulp therapy in permanent teeth. Epub 2020 Nov 5. International journal of paediatric dentistry, European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, The journal of evidence-based dental practice, By clicking accept or continuing to use the site, you agree to the terms outlined in our. This systematic review aims to illustrate the outcome of vital pulp therapy, namely direct pulp capping, partial pulpotomy, and full pulpotomy, in vital permanent teeth with cariously exposed pulp. PURPOSE This systematic review and meta-analysis assessed outcomes in primary teeth for the vital pulp therapy (VPT) options of indirect pulp therapy (IPT), direct pulp capping (DPC), and pulpotomy after a minimum of 12 months to determine whether one VPT was superior. The approaches include indirect pulp capping in deep caries cavities and direct pulp capping or pulpotomy in cases of pulp exposure. In the era of biology-driven endodontics, vital pulp therapies are regaining popularity as a valid clinical option to postpone root-canal treatment. Selection of the method used in vital pulp therapy relies on the degree of inflammation of the pulp. Methods: Electronic database MEDLINE via Ovid, PubMed, and Cochrane databases were searched. Ballal NV, Duncan HF, Rai N, Jalan P, Zehnder M. J Clin Med. This site needs JavaScript to work properly. Pulp Therapy Systematic Reviews The pulp therapy workgroup (Drs. Vital pulp therapy aims at maintaining the pulp tissue injured but vital. 4 Due to advances in science and technology, vital pulp treatment has changed over the last five years in regard to the procedures and materials used. Results: Thus, the use of capping materials that induce tissue regeneration is a great current trend. Systematic Review Registration Number: PROSPERO 2015: CRD42015006942. Partial or full pulpotomy were more reliable than direct pulp capping. NLM Coronal pulpotomy for cariously exposed permanent posterior teeth with closed apices: A systematic review and meta-analysis. Epub 2015 Dec 10. Systematic review consists of collecting unbiased Management of deep caries lesions with or without pulp involvement in primary teeth: a systematic review and network meta-analysis. 2020 Jun 15;10(3):300-308. doi: 10.4103/jispcd.JISPCD_69_19. direct contact with pulp [20]. A recent International Endodontic Journal Editorial suggested clinical diagnosis of pulp disease should be reassessed because of the poor correlation between clinical symptoms and pulp sensibility testing and the actual histological status of the pulp. Vital permanent teeth with cariously exposed pulp can be treated successfully with vital pulp therapy. Patents were related to endodontic/dental (bio)materials. This review identified studies in a PubMed search that provide evidence for vital pulp therapy (VPT) of mature permanent teeth with … In 2003, the only Cochran systematic review regarding vital pulp therapy for primary teeth stated that: “based on the 2020 Aug 31;17(17):6340. doi: 10.3390/ijerph17176340. Vital pulp therapy encompasses apexogenesis, pulpotomy, pulpal debridement, and direct and indirect pulp capping. Vital pulp therapy is a good treatment alternative when a provisional therapy is needed for a reason such as insufficient treatment time or limited patient finances. dentist. Hand searching was performed through reference lists of endodontic textbooks, endodontic-related journals, … This study aimed to systematically review the literature of animal studies to evaluate whether bioactive dentin proteins could improve vital pulp therapy success. Performing a topic sorting, 15 RCTs were about vital pulp therapy and 8 about anesthesia and pain. Decision-making when approaching clinical problems should be based on the best currently available evidence. Vital pulp therapy is performed to preserve the health status of the tooth and its ultimate position in the arch. Predictable vital pulp therapy depends on accurate determination of the pulpal status that will allow repair to occur. The indirect comparison of success rates for 4 follow-up periods and the indirect comparison of clinical factors influencing the success rate of each treatment were performed by z test for proportion (P < .05). CRD summary This review concluded that vital pulp therapy should be considered as an alternative to pulpectomy for vital permanent teeth with exposed pulp due to caries. Clipboard, Search History, and several other advanced features are temporarily unavailable. Pulpotomy is the favored method only if the coronal part of an exposed vital pulp is inflamed because of infiltration of microorganisms after carious or mechanical reasons, and the remaining radicular pulp is healthy [ 24 ]. Use of Vital Pulp Therapies in Primary Teeth with Deep Caries Lesions. The pulp Properties like biocompatibility and bioactivity are to be expected in dentistry-applied bioceramic materials for their use in vital pulp therapy [ 7 ]. One well-conducted economic evaluation from Germany found that direct pulp capping was cost-effective when compared with root canal in most cases, including when the willingness-to-pay ceiling value was adjusted (from 0 to 250 euro).  |  Background. Some features of the site may not work correctly. Munir A(1), Zehnder M(1), Rechenberg DK(1).  |  Introduction: This systematic review aims to illustrate the outcome of vital pulp therapy, namely direct pulp capping, partial pulpotomy, and full pulpotomy, in vital permanent teeth with cariously exposed pulp. J Dent. In this sense, many different materials are available in the market for pulp-capping purposes. Wound Lavage in Studies on Vital Pulp Therapy of Permanent Teeth with Carious Exposures: A Qualitative Systematic Review. Electronic database MEDLINE via Ovid, PubMed, and Cochrane databases were searched. 2012 Nov;143(11):1232-3. doi: 10.14219/jada.archive.2012.0069. The following databases were searched from 1960 to September 2016: MEDLINE, EMBASE, CENTRAL, EBSCO, ICTRP, Dissertation abstracts, and grey literature for parallel and split-mouth randomized controlled trials of at…. The pulp therapy workgroup has been working on two evidence-based systematic reviews: vital pulp therapy and non-vital pulp therapy. The Vital Pulp Therapy of Permanent Teeth: A Dental Practitioner's Perspective from Saudi Arabia. The key to the success of vital pulp therapy … PURPOSE 2020 Sep;21(3):112-113. doi: 10.1038/s41432-020-0128-0. VPT is a restorative dental procedure that aims to treat teeth with compromised dental pulp without the full removal or excavation of all healthy pulp tissue. Success of pulpotomy in mature permanent teeth with irreversible pulpitis: A systematic review. eliminate the infected or contaminated pulp and to reach the healthy vital pulp [2]. These procedures are performed routinely in primary and permanent teeth. Upon performing our systematic search there were only four randomized controlled trials that have compared pulpotomy and pulpectomy outcomes in vital primary incisors 9 , 15 , 20 , 21 . Alqaderi H, Lee CT, Borzangy S, Pagonis TC. This qualitative systematic review aimed to identify the types of pulp wound lavage and their influence on the vital pulp therapy of permanent human teeth with carious pulp exposure in all prospective controlled and randomized controlled clinical trials on vital pulp therapy. After pulp tissue removal, pulpotomy dressing agent is applied to the pulp surface, allowing the pulp to heal and the root to form. Search strategy and evidence inclusion criteria. Overall, the success rate was in the range of 72.9%-99.4%. METHODS 2016 Jan;44:1-7. doi: 10.1016/j.jdent.2015.12.005. • The most important factor that affects the success of … Munoz-Sanchez ML, Linas N, Decerle N, Nicolas E, Hennequin M, Cousson PY. This systematic review and meta-analysis assessed outcomes in primary teeth for the vital pulp therapy (VPT) options of indirect pulp therapy (IPT), direct pulp capping (DPC), and pulpotomy after a minimum of 12 months to determine whether one VPT was superior. Comparison of indirect pulp treatment and iRoot BP Plus pulpotomy in primary teeth with extremely deep caries: a prospective randomized trial. Conclusions: Systematic reviews and meta-analysis based on randomized controlled trials (RCTs), are the best reliable sources for suggesting and decisions in clinical dental practice making [21]. The weighted pooled success rate of each treatment was estimated in 4 groups: >6 months-1 year, >1-2 years, >2-3 years, and >3 years. 2002 Apr;28(1):29-37. doi: 10.1111/j.1747-4477.2002.tb00364.x. Biological Markers for Pulpal Inflammation: A Systematic Review Background and Objective Pulpitis is mainly caused by an opportunistic infection of the pulp space with commensal oral microorganisms. 2020 Jul 28;9(8):2408. doi: 10.3390/jcm9082408. Elmsmari F, Ruiz XF, Miró Q, Feijoo-Pato N, Durán-Sindreu F, Olivieri JG. successful outcome of vital pulp therapy in vital teeth with cariously exposed pulp with signs and symptoms of irreversible pulpitis with periapical lesions (17–20). J Am Dent Assoc. Outcome of Partial Pulpotomy in Cariously Exposed Posterior Permanent Teeth: A Systematic Review and Meta-analysis. 2020 Mar-Apr;23(2):121-125. doi: 10.4103/JCD.JCD_179_19. This study aims to evaluate clinically and radiographically the pulp repair after the use of dentin-pulp biostimulation membrane in primary teeth. Applied to vital pulp therapy, bioceramic materials can be used in cases of pulp exposition from trauma, caries or other mechanical causes, as direct pulp cappers . Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Mineral The random effect method of weighted pooled success rate of each treatment and the 95% confidence interval were calculated by the DerSimonian-Laird method. Doumani MD, Arnous WA, Alsafadi MF, Alnazer HA, Alanazi SM, Alotaibi KS, Al-Ammari AI. Vital pulp therapy comprises modalities such as direct pulp capping, pulpotomy, and an emerging family of regenerative pulp therapy; judicious application of these procedures enables apical closure and root development in immature permanent teeth by preserving the vitality of pulp tissues . Methods: Coll, Marghalani, Seale and Vargas) met for two days at headquarters in November to review the meta-analyses of over 50 randomized controlled trials of pulp therapy. Hand searching was performed through reference lists of endodontic textbooks, endodontic-related journals, and relevant articles from electronic searching. J Endod. Subsequently, pulpotomy is kind of a vital pulp therapy methods when the coronal portion of the inflamed pulp is removed and the radicular pulp is preserved to ensure the pulp vitality [9]. You are currently offline. A Combination of Full Pulpotomy and Chairside CAD/CAM Endocrown to Treat Teeth with Deep Carious Lesions and Pulpitis in a Single Session: A Preliminary Study. Depending on the state of inflammation, different treatment regimes are … 17 ):6340. doi: 10.14219/jada.archive.2012.0069 with cariously exposed permanent teeth with extremely deep caries Lesions to preserve health! 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